goji

More than 18 million people in the United States have diabetes. And nearly one-third of them are undiagnosed. This can be devastating, as diabetes is the main cause of kidney failure, limb amputation, and new onset blindness in American adults.

People with diabetes are also two to four times more likely than people without diabetes to develop heart disease. In fact, 65 percent of diabetics die from heart attack or stroke.

Diabetes mellitus is a condition in which the amount of glucose (sugar) in the blood is too high because the body cannot use it properly. Glucose comes from the digestion of starchy foods such as bread, rice, potatoes, chapatis, yams and plantain, from sugar and other sweet foods, and from the liver which makes glucose. Diabetes is a disorder that affects the way your body deals with the foods you eat. Normally, carbohydrate foods are broken down into the sugar glucose, which travels in the blood (hence the name blood sugar) until it reaches your cells, where it is taken in and used for growth and energy. For this to happen, however, the hormone insulin must be present. Produced by the pancreas, insulin acts as a key that unlocks cells so that they can receive blood glucose.

Insulin works like a key to open the door of the cells so glucose – the fuel you get from food – can come inside and be converted into energy – cause serious complications and premature death. Insulin is vital for life. It is a hormone produced by the pancreas that helps the glucose to enter the cells where it is used as fuel by the body.

The main symptoms of untreated diabetes are increased thirst, going to the look all the time – especially at night, extreme tiredness, weight loss, genital itching or regular episodes of thrush, and blurred vision.

In diabetes, either the pancreas may produce insufficient insulin, or the body has lost its ability to use it effectively (insulin resistance). Glucose builds up in the blood, overflows into the urine, and passes out of the body without fulfilling its role as the body’s main source of fuel.

Two types of diabetes:

Type 1 diabetes develops if the body is unable to produce any insulin. This type of diabetes usually appears before the age of 40. It is treated by insulin injections and diet and regular exercise is recommended.  Type 2 diabetes develops when the body can still make some insulin, but not enough, or when the insulin that is produced does not work properly (known as insulin resistance). In most cases this is linked with being overweight. This type of diabetes usually appears in people over the age of 40, though in South Asian and African-Caribbean people often appear after the age of 25. However, recently, more children are being diagnosed with the condition, some as young as seven.

Type 2 diabetes is treated with lifestyle changes such as a healthier diet, weight loss and increased physical activity. Tablets and/or insulin may also be required to achieve normal blood glucose levels.

The main aim of treatment of both types of diabetes is to achieve blood glucose, blood pressure and cholesterol levels as near to normal as possible. This, together with a healthy lifestyle, will help to improve wellbeing and protect against long-term damage to the eyes, kidneys, nerves, heart and major arteries.

Managing Diabetes: Begin with the ABCs

The National Diabetes Education Program suggests that you reduce your risk of heart disease and stroke by working with your health care team to monitor three critical factors, which they have named the Diabetic ABCs.

“A” is for the A1C test.

This is a number that shows how well your blood glucose has been controlled over the last 3 months. Bad glucose control can hurt your eyes, kidneys and feet. The goal for most people is an A1C of less than 7. It should be checked at least twice a year.

A 1998 research study showed that increased in blood pressure could be prevented significantly by goji’s master molecule polysaccharides. Polysaccharides are very long-chain sugar molecules that provide nourishment for macrophages, the large white blood cells which are an important component of the body’s defense system against invading microbes and the malignant cells which form tumors.

Four polysaccharides discovered in Goji berries have not been found in any other fruit. The Goji polysaccharides enhance the body’s production of human growth hormone (HGH), which helps build muscle and repair skin cells. The LBP polysaccharide complex unique to Goji berries has been found to be a powerful secretagogue – a substance that stimulates the secretion of human growth hormone (HGH) by the pituitary gland.

One research study in China showed that the LBP polysaccharide facilitated the proliferation of stem cells and increased the number of monocytes in bone marrow. The LBP polysaccharide helps the monocytes convert to matured leukocytes.

“B” is for blood pressure.

The goal for most people is 130/80. High blood pressure can cause heart attack, stroke and kidney disease.

“C” is for cholesterol.

Bad cholesterol (LDL) can oxidize and clog blood vessels, causing heart attack or stroke. Good cholesterol (HDL) helps to lower bad cholesterol. The goal for most people is LDL under 100 and HDL over 40.

Goji contains eta-sitosterol, which has been shown to lower cholesterol levels.  Its antioxidants keep cholesterol from oxidizing and forming arterial plaques. Goji increases exercise tolerance, stamina, and endurance.  It also helps to eliminate fatigue, especially when receiving from illness.

acne

More often than not, female population is the most common target of the troublesome acne dilemma. This is not because acne is picky on who it should affect. This is because women are more prone to hormonal changes. Women, starting from their teenage years up to adulthood and from all walks of life are not exempted from having hormonal changes and acne breakouts. Even the most popular female celebrity is not excused from having pimple. They just look flawless in televisions and magazines because they know how to conceal it. There are many stages and events in a woman’s life where there is a change in hormone and acne is the obvious side effect.

When a female reached her adolescent period, it the beginning of the changes in hormone and acne starts to appear. During this stage the male hormonal levels increase. This goes for both male and female since both genders have androgens. When there is a high level of androgen, it would trigger the oil ducts to do its function at a faster rate. This results to overproduction of skin’s natural oil. Eventually, the pores will become clogged by the overproduced oil causing the formation of skin acne. Once it made contact with harsh environmental factors such as bacteria coming from different kinds of pollutants, filthy viruses will start to breed in. This is the start of inflamed and hideous acne.

Every month (for those who have a regular menstrual period), women feel and see different signs and symptoms that their monthly period is fast approaching. Mood swings and tenderness of breasts are caused by the change in hormone and acne appearance is also a visible sign. It is just like during the stage of adolescence where androgens are most likely to increase. However, not all women experience the same dilemma over and over again during the course of the upcoming menstrual period. Some says that taking oral contraceptives can help prevent acne appearance even if hormonal changes happen. Of course, this is not applicable to pregnant women.

During the nine-month long period of pregnancy, women are also prone to changes in her hormone and acne breakouts. Others say that this is a sign of bearing a baby boy since the androgen level in her body is fast increasing. Although these events are certainly inevitable, there are still different ways how to cure and prevent acne, but not the raging hormone.

ovarian-cancer

Two Percent of All Female Newborns in the United States Are at Risk of Getting Ovarian Cancer.

As many as 30,000 U.S. women will be diagnosed with ovarian cancer this year. In 2006, between 15,000 and 16,000 women are likely to die from this silent killer. Ovarian cancer is the 5th leading cause of death among women, and it is responsible for about five percent of all cancer deaths. Chances are your doctor may have misdiagnosed you. That is often the case. A recent British study found 60 percent of all U.K. general practitioners had misdiagnosed their patients. Three-quarters of British doctors surveyed incorrectly assumed that symptoms only occurred in the late stages of ovarian cancer. Based upon that information, it should be no surprise that Britain has one of the lowest survival rates for ovarian cancer in the Western World – of 6,800 cases diagnosed each year, more than 4,600 die.

A similar discovery was made by University of California researchers, who announced last year, “Four in 10 women with ovarian cancer have symptoms that they tell their doctors about at least four months — and as long as one year — before they are diagnosed.” According to their study of nearly 2,000 women with ovarian cancer, the researchers discovered physicians:

• First ordered abdominal imaging or performed gastrointestinal procedures instead of the more appropriate pelvic imaging and/or CA-125 (a blood test that can detect ovarian cancer).

• Only 25 percent of patients, who reported ovarian cancer symptoms four or more months before diagnosis, were given pelvic imaging or had CA-125 blood tests.

Patients with early symptoms are frequently misdiagnosed. Abdominal imaging or diagnostic gastrointestinal studies are less likely to detect ovarian cancer. According to the American Cancer Society’s website, “The most common symptom is back pain, followed by fatigue, bloating, constipation, abdominal pain and urinary urgency. These symptoms tend to occur very frequently and become more severe with time. Most women with ovarian cancer have at least two of these symptoms.”

By the time a woman reaches the fourth stage of ovarian cancer, her first-line treatment is often Carboplatin, Paclitaxel and Cisplatin as the specific chemotherapy for ovarian cancer. In the first stage, cancer is contained inside one or both ovaries. By stage two, the cancer has spread into the fallopian tubes or other pelvic tissues, such as the bladder or rectum. When the cancer has spread outside the pelvis area into the abdominal cavity, especially when tumor growths are larger than two centimeters on the lining of the abdomen, then ovarian cancer has reached stage three. The fourth and final stage of ovarian cancer is reached when the cancer has spread into other body organs, such as the liver or lungs.

If detected early, survival rates can be as high as 90 percent. Detected in the advanced stage, the survival rate falls to between 30 and 40 percent. Various imaging tests such as computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, and ultrasound studies can confirm whether a pelvic mass is present. A laparoscopy can help a doctor look at the ovaries and other pelvic tissue to in order to plan out a surgical procedure, or to determine the stage of the ovarian cancer. A biopsy, or tissue sampling, would confirm if there is cancer in your pelvic region, and would help determine how advanced it is. An elevated CA-125 blood test typically suggests the cancer has progressed to the advanced stage.

About 50 percent of ovarian cancer patients are already at an advanced stage by the time a correct diagnosis is made. Only 10 to 14 percent of women with advanced cancer are likely to survive more than five years.

Evaluation of Therapies

While research shows drinking black (or green) tea or taking the herbal supplement gingko biloba may be useful, as a preventative measure, or to reduce risk, a woman has few choices when her cancer has moved to the advanced stage. In the first stage, a woman faces surgical removal of the tumor, and possibly one or both ovaries, to increase her chances of survival. Beyond that, her choice is chemotherapy.

One major problem with chemotherapy is the side effects. The more advanced the cancer, the weaker one may be, reducing the survival rate potential. Survival rates have not changed very much over the past fifteen years. Chemotherapy can increase survival time by as much as 50 percent. But, quality of life suffers. The side effects and increased toxicity, accompanying chemotherapy, reduce how one spends the prolonged survival time.

Some of Paclitaxel’s minor side effects, as reported by Medline Plus, may include nausea, vomiting, loss of appetite, change in taste, thinned or brittle hair, pain in the joints of the arms or legs, changes in the color of nails, and/or tingling in the hands or toes. More serious side effects may include mouth blistering or fatigue. Some alarming side effects could include unusual bleeding or bruising, dizziness, shortness of breath, severe exhaustion, chest pain, or difficulty swallowing. The most common side effect of Paclitaxel is a decrease of blood cells.

Carboplatin has its own list of side effects. It can reduce platelet production, which can interfere with your blood’s ability to clot. You may become anemic, feeling tired or breathless. Nausea, vomiting, loss of appetite and a general feeling of weakness are common with this chemotherapeutic agent.

The latest breed of drugs, such as Eli Lilly’s Gemzar, are hardly getting praise. On March 10th, the Food and Drug Administration (FDA) said it was skeptical of the benefits Eli Lilly’s Gemzar, which was being used with Carboplatin to treat ovarian cancer patients. The FDA felt the 2.8 months increased survival time, provided by the Gemzar/Carboplatin combination failed to offset the treatment’s increased toxicity.

In January, the New England Journal of Medicine reported on a remarkable new delivery system of chemotherapy, called the “intra-abdominal, or intraperitoneal, chemotherapy. Those who received the “belly bath” as it is now being called by the media can survive 16 months longer than those receiving intravenous chemotherapy. The major drawback is that 60 percent of the women in the study were unable to complete all six cycles of this chemotherapy. Those who did survived longer, but only two in every five women were able to advance to the end phase of the therapy.

One novel approach, now in Phase III trials at more than 60 research centers across the United States, is OvaRex ® MAb, a murine monoclonal antibody, a type of biotech drug derived from mouse cells. It is being tested by highly regarded United Therapeutics, based in Silver Springs, Maryland. Their lead drug Remodulin, an injection which treats pulmonary arterial hypertension, is currently being marketed inside and outside the United States. More than $32 million has been spent researching, and on the development of, OvaRex and may have it available on the market by 2008.

OvaRex was developed in Canada by a company called ViRexx Medical Corp, and first tested in that country. According to Dr. Lorne Tyrrell, Chief Executive of ViRexx, “The whole study has been set up with the FDA. This is a study where the drug has been given fast track approval and orphan drug status.” Dr. Tyrrell is also on leave (until OvaRex become commercially available) as a Professor of Medical Microbiology and Immunology at the University of Alberta, and Director of the National Centre of Excellence for Viral Hepatitis Research.

OvaRex was tested in Canada, prior to the current Phase III trials in the U.S. “There have been a number of patients that have received OvaRex,” said Dr. Tyrrell, “We’ve had really no adverse effects from these patients.” Dr. Tyrrell explained the procedure, “After being injected intravenously, OvaRex binds to an antigen circulating in the blood.” An antibody’s general purpose is to neutralize an antigen. After an OvaRex injection, the murine monoclonal antibody binds to the CA-125 antigen.

In a way the body is tricked. But, the body is tricked in order to help “save” itself from the harmful antigen. When the OvaRex antibody is bound to the CA-125 antigen, the new combination is identified as a harmful unit. Before then, the antigen wanders through the body, without alerting the body’s defense systems, the dendritic cells, to attack and destroy the harmful antigen. Because the body is trained to identify and zero in on a foreign protein, in this case a mouse protein, it alerts the dendritic cells. Until then, the dendritic cells “tolerate” the cancerous cells. The tolerance is what permits the cancer to spread throughout the body.

OvaRex seeks to break that tolerance. The murine monoclonal antibody is designed to target and bind exclusively to free floating CA-125 antigen. The dendritic cells refuse to tolerate the foreign protein. When the antibody binds with the free-floating antigen, the dendritic cells recognize the complex (antibody plus antigen) as being foreign and engulf the new unit. The dendritic cells break down the key proteins of this unit, presenting all parts on the cells surface. At the point, the body’s killer T-Cells are alerted to fight the internal threat to the body. Once activated, the T-Cells will replicate and create more killer T-Cells. Any tumor cells expressing the CA-125 antigen is targeted for destruction. The army of T-Cells move to attack the ovarian cancer tumor.

The principle behind OvaRex is to re-program the immune system to harness the body’s defenses to prevent the growth and spread of the ovarian cancer. Will it cure ovarian cancer? “In most cases, it will be a delay,” explained Dr. Tyrrell. “However, I think that, and everyone hopes that, often in some of these tumors, you’re making incremental progress through careful clinical trials and adding new therapy. Each thing we do that improves the outcome when you start to look at the long term benefits of these, we hope that one day we will be able to cure this disease. We think this is a step. This has the potential to be an important step at helping to stimulate immune response to achieve a better outcome. Hopefully, one day we can improve that to where it is a cure.”

health-insurance

Indemnity health insurance plans are more regularly known as traditional health insurance plans. These health insurance plans can be costly but often cover most health problems that may arise, while other insurance plans exclude some illnesses or diseases from their coverage. Some disadvantages to indemnity plans are that they do not usually cover preventative health care like physicals, and traditional health insurance plans often cover only a percentage of your bill. Research the advantages and disadvantages to indemnity health insurance when you are considering health insurance options.

While the disadvantages may seem problematic, there are many advantages to indemnity health insurance plans. You may have a higher monthly premium and you may need to pay upfront costs and submit claims paperwork, but your deductible will be more manageable and your coverage will be wider. Some health insurance plans will not cover certain medical expenses or care, but indemnity plans often do.

Another benefit of indemnity health insurance plans that many people desire is the freedom to choose your own physician. While other health insurance plans offered by the insurance industry limit your choice of physicians and hospitals to a list of preferred providers, indemnity insurance will cover any physician or hospital. This benefit may seem unworthy of mention, but there has been more than one instance where a mother finds that her son or daughter’s pediatrician is not in their preferred provider network and has to search for another pediatrician. This also means that you can see a specialist without having to consult with your primary care physician first.

Overall, indemnity health insurance plans also offer you the best emergency medical coverage in the industry. While preferred provider organizations (PPOs) or point-of-service (POS) plans limit the physician you can see to a list of network physicians and hospitals, the freedom of choosing any physician is nationwide with indemnity health insurance plans. This means that if you are traveling across the country and have an accident or a medical emergency, you can go to the nearest hospital or see the closest physician without worrying about the expense. There have been instances where hospitals or physicians will either refuse to treat patients or treat them only minimally because the hospital or physician is not inside the plan’s preferred provider network – meaning that the patient’s health insurance will only cover a small part of the expense and the patient is liable to pay the rest of the bill. This is a risky financial situation for the physician and/or hospital since patients are often unable to fully pay costly medical bills. With indemnity health insurance plans, this is almost never the case. Consider this and the other benefits of indemnity health insurance when choosing the plan that is right for you.

acne scar

Acne is a universal disorder which affects 80 percent of young people and about 5 percent of adults. When acne becomes irritated and then heals, it leaves behind marks called acne scars. These scars if left untreated can remain on the skin for years. They are removed by the development of new skin layers. This is where acne scar removers come into play. They make the process of skin renewal very fast and effectively lighten the scarred skin.

Acne scars are classified by their appearance, size and shape. They can also be classified as early or permanent scars depending on the length of time they have been around. The newer scars tend to respond to topical medications much better than older scars. Most permanent scars can be treated by a combination of topical solutions and surgical procedures that enhances skin resurfacing.

There are many acne scar remover in the market today. This article aims to provide you with a partial list of some of these scar removers as well as give you an option on alternative ways to remove acne scars.

Let’s start with the natural ways of scar removal. This method may take longer than most topical medications and surgical procedures but you can be assured that it won’t harm or irritate your skin any further as it only uses natural ingredients.

Drinking 8 glasses of water a day may start to sound like an all-cure for any ailment but it really helps in minimizing acne scars because the skin needs moisture to remain smooth and elastic. It also helps in the skin’s renewal process. Other natural methods include eating vegetables like carrots, cucumber, spinach and fresh fruits. The vitamins and minerals in these food help maintain total skin health. Some also use natural essential oils as topical treatments to help in acne scar reduction. This includes tea tree oil, lavender oil and lemon oil. They are used to clean the skin and remove dead skin layers.

Mederma which is made from original mixture of botanical extracts and can help remove scars like stretch marks, burn scars, acne scars and surgical scars. Healscars is another topical treatment that has a powerful regenerative property to help in faster skin layer renewal. Furtheremore, Bioskincare is not only an acne scar remover but also helps reduce the appearance of other scars making the skin look softer and healthier.

Lastly, Miracle Cure Duo is a combination of acne treatment and skin protection that gives you a powerful and complete acne scar remover cure.